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Molecular laboratories include Real-time PCR and FISH techniques in oncology.
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LAB Tests
REAL-TIME PCR
Single gene mutation – Tissue Block
EGFR 42 mutations (Super-ARMS)
SCREENS FOR
EGFR Exon 18 G719X, Exon 19 deletions, Exon 20-Ins S768I/T790M, Exon 21 L858R/L861Q mutations in FFPE Block
TURNAROUND TIME
3 days
KRAS 19 mutations
SCREENS FOR
Exon 2, 3 and 4 / Codon 12, 13, 59, 61, 117, and 146
TURNAROUND TIME
3 days
NRAS 16 mutations
SCREENS FOR
Exon 2, 3 and 4 / Codon 12, 13, 59, 61, 117, and 146
TURNAROUND TIME
3 days
BRAF 6 mutations (V600 mutation)
SCREENS FOR
V600E1, V600K, V600E2, V600R, V600D1 and V600D2
TURNAROUND TIME
3 working days
REAL-TIME PCR
Single gene mutation – Blood
EGFR 42 mutations (Super-ARMS)
SCREENS FOR
Exon 18 G719X, Exon 19 deletions, Exon 20-Ins S768I/T790M, Exon 21 L858R/L861Q mutations in plasma
TURNAROUND TIME
3 days
REAL-TIME PCR
Panel gene – Tissue Block
Colon cancer panel : KRAS + NRAS + BRAF
WHO : Colorectal Cancer patients
SCREENS FOR
KRAS19, NRAS16 and BRAF6 mutations
TURNAROUND TIME
3 days
Complete RAS mutation for Colon cancer Panel : KRAS + NRAS
WHO : Colorectal Cancer patients
SCREENS FOR
KRAS19 and NRAS16 mutations
TURNAROUND TIME
3 days
Swift CA Lung Panel
SCREENS FOR
11 Driver genes ( ALK + NTRK 1/2/3 + ROS1 + MET + RET
+ EGFR + HER2 + BRAF + KRAS ) 167 Variants
TURNAROUND TIME
7 days
Swift Tiny Panel
SCREENS FOR
9 Driver genes ( ALK, ROS1, RET, HER-2, KRAS, NRAS, BRAF, PIK3CA )
TURNAROUND TIME
7 days
FISH Technique
Fluorescence in situ Hybridization
ALK break apart
SAMPLE : FFPE or Unstained slide
TURNAROUND TIME
7 days
ROS1 break apart
SAMPLE : FFPE or Unstained slide
TURNAROUND TIME
7 days
HER2 amplification
SAMPLE : FFPE or Unstained slide
TURNAROUND TIME
7 days
Swift CA Lung Panel
SCREENS FOR
11 Driver genes ( ALK + NTRK 1/2/3 + ROS1 + MET + RET+ EGFR + HER2 + BRAF + KRAS )
167 Variants
TURNAROUND TIME
7 days
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